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High cost and insurance restrictions are common, with many plans requiring step therapy, higher BMI, or documented inability to lose weight by other methods before approval. Do GLP-1 drugs replace the need for arthritis or autoimmune medications

Injection drug use can also foster the spread of human immunodeficiency virus (HIV) along with hepatitis B and C, all of which can lead to acute or chronic kidney injury over time

Energy metabolism and lipid metabolism are intimately connected, with many of the dysregulated lipids identified in these patients being essential components of cellular membranes and having significant roles in energy metabolism (Hu et al., 2022)